Caenorhabditis elegans gelsolin-like protein 1 is a novel actin filament-severing protein with four gelsolin-like repeats.

@article{Klaavuniemi2008CaenorhabditisEG,
  title={Caenorhabditis elegans gelsolin-like protein 1 is a novel actin filament-severing protein with four gelsolin-like repeats.},
  author={Tuula Klaavuniemi and Sawako Yamashiro and Shoichiro Ono},
  journal={The Journal of biological chemistry},
  year={2008},
  volume={283 38},
  pages={26071-80}
}
The gelsolin family of proteins is a major class of actin regulatory proteins that sever, cap, and nucleate actin filaments in a calcium-dependent manner and are involved in various cellular processes. Typically, gelsolin-related proteins have three or six repeats of gelsolin-like (G) domain, and each domain plays a distinct role in severing, capping, and nucleation. The Caenorhabditis elegans gelsolin-like protein-1 (gsnl-1) gene encodes an unconventional gelsolin-related protein with four G… CONTINUE READING