Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium.

Abstract

We used the ability of Salmonella enterica serovar Typhimurium to colonize the gut of Caenorhabditis elegans to measure the fitness costs imposed by antibiotic resistance mutations. The fitness costs determined in the nematode were similar to those measured in mice, validating its use as a simple host model to evaluate bacterial fitness.

Cite this paper

@article{Paulander2007CaenorhabditisEA, title={Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium.}, author={Wilhelm Paulander and Alexandra Pennhag and Dan I. Andersson and Sophie Maisnier-Patin}, journal={Antimicrobial agents and chemotherapy}, year={2007}, volume={51 2}, pages={766-9} }