Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

  title={Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology},
  author={Maxwell C. K. Leung and Phillip L. Williams and Alexandre Benedetto and Catherine S S Au and Kirsten J. Helmcke and Michael Aschner and Joel N. Meyer},
  journal={Toxicological Sciences},
  pages={5 - 28}
The nematode Caenorhabditis elegans has emerged as an important animal model in various fields including neurobiology, developmental biology, and genetics. Characteristics of this animal model that have contributed to its success include its genetic manipulability, invariant and fully described developmental program, well-characterized genome, ease of maintenance, short and prolific life cycle, and small body size. These same features have led to an increasing use of C. elegans in toxicology… CONTINUE READING
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Caenorhabditis elegans gene, Numr-1, assembles into nuclear stress granules after cadmium treatment

  • B. Tvermoes, J. H. Freedman
  • In SOT Meeting March 16-20,
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