Cadmium toxicity in glutathione mutants of Escherichia coli.

  title={Cadmium toxicity in glutathione mutants of Escherichia coli.},
  author={Kerstin Helbig and Cornelia S. Gro\sse and Dietrich H Nies},
  journal={Journal of bacteriology},
  volume={190 15},
The higher affinity of Cd(2+) for sulfur compounds than for nitrogen and oxygen led to the theoretical consideration that cadmium toxicity should result mainly from the binding of Cd(2+) to sulfide, thiol groups, and sulfur-rich complex compounds rather than from Cd(2+) replacement of transition-metal cations from nitrogen- or oxygen-rich biological compounds. This hypothesis was tested by using Escherichia coli for a global transcriptome analysis of cells synthesizing glutathione (GSH; wild… CONTINUE READING


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Role of the extracytoplasmic function protein family sigma factor RpoE in heavy metal resistance of Escherichia coli

  • M. Egler, C. Grosse, G. Grass, D. H. Nies
  • J. Bacteriol
  • 2005
Highly Influential
5 Excerpts

Arsenic metabolism in prokaryotic and eukaryotic microbes, p. 371–406

  • H. Bhattacharjee, B. P. Rosen
  • Molecular microbiology of heavy metals,
  • 2007
1 Excerpt

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