Cadmium stimulates MAPKs and Hsp27 phosphorylation in bovine adrenal chromaffin cells.

@article{Leal2007CadmiumSM,
  title={Cadmium stimulates MAPKs and Hsp27 phosphorylation in bovine adrenal chromaffin cells.},
  author={Rodrigo Bainy Leal and Tha{\'i}s Posser and Ana Paula Rigon and Camila Souto Oliveira and Carlos Alberto Saraiva Gonçalves and Daniel Pens Gelain and Peter Dunkley},
  journal={Toxicology},
  year={2007},
  volume={234 1-2},
  pages={34-43}
}
Cadmium (Cd(2+)) is a common environmental pollutant, which is widely used in industry and is a constituent of tobacco smoke. Exposure to this heavy metal has been linked to a wide range of detrimental effects on mammalian cells. In this study, the action of Cd(2+) on protein phosphorylation in bovine adrenal chromaffin cells (BACCs) was examined. Cells were incubated with (32)Pi in the presence of Cd(2+) (1-50 microM) and proteins were separated by one- or two-dimensional electrophoresis. An… CONTINUE READING