Cadmium induces anemia through interdependent progress of hemolysis, body iron accumulation, and insufficient erythropoietin production in rats.

@article{Horiguchi2011CadmiumIA,
  title={Cadmium induces anemia through interdependent progress of hemolysis, body iron accumulation, and insufficient erythropoietin production in rats.},
  author={Hyogo Horiguchi and Etsuko Oguma and Fujio Kayama},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2011},
  volume={122 1},
  pages={
          198-210
        }
}
Cadmium is a toxic heavy metal and distributed widely in the environment. In addition to damaging the liver, kidneys, and bone, cadmium causes anemia through hemolysis, iron deficiency, and insufficient erythropoietin (EPO) production (renal anemia) along with changes in iron metabolism. Here, we investigated the role of iron in the interdependent progress of three types of anemia in cadmium-injected rats fed iron-sufficient or iron-deficient diets for 1 or 3 months. Cadmium injections for 1… 
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Cadmium Induces Iron Deficiency Anemia through the Suppression of Iron Transport in the Duodenum.
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