Cadmium-induced IL-6 and IL-8 expression and release from astrocytes are mediated by MAPK and NF-κB pathways.

@article{Phuagkhaopong2017CadmiuminducedIA,
  title={Cadmium-induced IL-6 and IL-8 expression and release from astrocytes are mediated by MAPK and NF-κB pathways.},
  author={Suttinee Phuagkhaopong and Dusadee Ospondpant and Thitima Kasemsuk and Nathawut Sibmooh and Sunhapas Soodvilai and Christopher Power and Pornpun Vivithanaporn},
  journal={Neurotoxicology},
  year={2017},
  volume={60},
  pages={82-91}
}
Chronic exposure to cadmium has been linked to brain cancers, learning disabilities and memory deficits. Previous studies of cadmium toxicity in the central nervous system report cadmium induces oxidative stress in neurons and astrocytes. In the peripheral system, cadmium promotes interleukin-6 (IL-6) and IL-8 production and release. Elevation of IL-6… CONTINUE READING