Cadmium in vivo causes disruption of tight junction-associated microfilaments in rat Sertoli cells.

@article{Hew1993CadmiumIV,
  title={Cadmium in vivo causes disruption of tight junction-associated microfilaments in rat Sertoli cells.},
  author={K W Hew and G L Heath and Azad Jiwa and Michael J. Welsh},
  journal={Biology of reproduction},
  year={1993},
  volume={49 4},
  pages={840-9}
}
Ten-week-old male Sprague-Dawley rats were injected i.p. with cadmium chloride solution in a single dose of 0 or 1.0 mg/kg BW. At 4, 24, 48, and 72 h after injection, testes of the animals were collected, detunicated, and fixed in 10% formalin. Individual seminiferous tubules were isolated and the stages of the cycle of the seminiferous epithelium were determined through use of transillumination under a stereomicroscope. The tubules were stained with rhodamine-phalloidin, mounted on glass… CONTINUE READING
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