Cadmium Mimics Estrogen-Driven Cell Proliferation and Prolactin Secretion from Anterior Pituitary Cells

@inproceedings{Ronchetti2013CadmiumME,
  title={Cadmium Mimics Estrogen-Driven Cell Proliferation and Prolactin Secretion from Anterior Pituitary Cells},
  author={Sonia Alejandra Ronchetti and Eliana Andrea Miler and Beatriz Hayd{\'e}e Duvilanski and Jimena Paula Cabilla},
  booktitle={PloS one},
  year={2013}
}
Cadmium (Cd) is a heavy metal of considerable occupational and environmental concern affecting wildlife and human health. Recent studies indicate that Cd, like other heavy metals, can mimic effects of 17β-estradiol (E2) involving E2 receptor (ER) activation. Lactotrophs, the most abundant cell type in anterior pituitary gland, are the main target of E2, which stimulates cell proliferation and increases prolactin secretion through ERα. The aim of this work was to examine whether Cd at nanomolar… CONTINUE READING
4
Twitter Mentions

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Overview of Cadmium Thyroid Disrupting Effects and Mechanisms

  • International journal of molecular sciences
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

Potential role of estrogen in maintaining the imbalanced sympathetic and sensory innervation in endometriosis

Yanchun Liang, Shuzhong Yao
  • Molecular and Cellular Endocrinology
  • 2016
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 48 REFERENCES

Radioimmunoassay for rat prolactin.

  • Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1969
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Cadmium--a metallohormone?

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Potential for effects of land contamination on human health. 1.The case of cadmium.

  • Journal of toxicology and environmental health. Part B, Critical reviews
  • 2012
VIEW 1 EXCERPT

The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not?

  • Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
  • 2012
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…