Cadherin engagement protects human β-cells from apoptosis.


The aim of this study was to assess the expression of different types of cadherins in human islets and their role in human β-cell apoptosis. Expression of E-, N-, and P-cadherins was studied by immunofluorescence on pancreas sections and islet cells, and by Western blotting on protein extracts of isolated islets and islet cells. The effects of specific… (More)
DOI: 10.1210/en.2011-1286


8 Figures and Tables