Cadherin defects in inherited human diseases.

@article{ElAmraoui2013CadherinDI,
  title={Cadherin defects in inherited human diseases.},
  author={Aziz El-Amraoui and Christine Petit},
  journal={Progress in molecular biology and translational science},
  year={2013},
  volume={116},
  pages={361-84}
}
The tight control of cell-cell connectivity mediated by cadherins is a key issue in human health and disease. The human genome contains over 115 genes encoding cadherins and cadherin-like proteins. Defects in about 21 of these proteins (8 classical, 5 desmosomal, 8 atypical cadherins) have been linked to inherited disorders in humans, including skin and… CONTINUE READING