CadA negatively regulates Escherichia coli O157:H7 adherence and intestinal colonization.

@article{VzquezJurez2008CadANR,
  title={CadA negatively regulates Escherichia coli O157:H7 adherence and intestinal colonization.},
  author={Roberto Carlos V{\'a}zquez-Ju{\'a}rez and Jeeba A. Kuriakose and David A. Rasko and Jennifer M. Ritchie and Melissa M. Kendall and Terry Slater and Mala Sinha and Bruce A. Luxon and Vsevolod L. Popov and Matthew K Waldor and Vanessa G Sperandio and Alfredo G Torres},
  journal={Infection and immunity},
  year={2008},
  volume={76 11},
  pages={5072-81}
}
Adherence of pathogenic Escherichia coli strains to intestinal epithelia is essential for infection. For enterohemorrhagic E. coli (EHEC) serotype O157:H7, we have previously demonstrated that multiple factors govern this pathogen's adherence to HeLa cells (A. G. Torres and J. B. Kaper, Infect. Immun. 71:4985-4995, 2003). One of these factors is CadA, a lysine decarboxylase, and this protein has been proposed to negatively regulate virulence in several enteric pathogens. In the case of EHEC… CONTINUE READING
14 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…