CacyBP/SIP protein is important for the proliferation of human glioma cells.

@article{Shi2014CacyBPSIPPI,
  title={CacyBP/SIP protein is important for the proliferation of human glioma cells.},
  author={Hengliang Shi and Yong Gao and Yuan Tang and Yuxuan Wu and Hui Gong and Jin Zhou Du and Bao Zheng and Jinxia Hu and Qiong Shi and Rutong Yu},
  journal={IUBMB life},
  year={2014},
  volume={66 4},
  pages={286-91}
}
Recently, calcyclin-binding protein or Siah-1-interacting protein (CacyBP/SIP), a component of a novel ubiquitinylation pathway, could regulate the β-catenin degradation (Fukushima et al., Immunity 2006, 24, 29-39). However, the potential role of CacyBP/SIP itself in human glioma cells has not been clarified. Here, we found that CacyBP/SIP was expressed highly in human glioma tissues. Silencing of CacyBP/SIP by short-hairpin RNA severely suppressed the proliferation of human glioma cell U251… CONTINUE READING
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