Cacofurans A and B, new furanoditerpenes from a marine sponge.

@article{Tanaka2001CacofuransAA,
  title={Cacofurans A and B, new furanoditerpenes from a marine sponge.},
  author={Junichi Tanaka and Gerard Marriott and Tatsuo Higa},
  journal={Journal of natural products},
  year={2001},
  volume={64 11},
  pages={1468-70}
}
Two new labdane-class diterpenes, cacofurans A (1) and B (2), have been isolated from a sponge Cacospongia sp. Their structures were determined by analyzing spectroscopic data, by chemical transformations, and by X-ray diffraction. Cacofurans 1 and 2 inhibited the development of fertilized sea urchin eggs at concentrations of 0.5 and 5 microg/mL and showed an actin-disrupting effect on the NBT-II cell line at 10 microg/mL.