Cachexia: a therapeutic approach beyond cytokine antagonism.

Abstract

Cachexia is seen in a number of chronic diseases, and it is always associated with a poor prognosis. Irrespective of etiology, the development of cachexia appears to share a common pathophysiological pathway. This includes induction of proteasome-dependent myofibril-degradation, which is thought to be secondary to stimulation by enhanced levels of pro… (More)

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Cite this paper

@article{Haehling2002CachexiaAT, title={Cachexia: a therapeutic approach beyond cytokine antagonism.}, author={Stephan von Haehling and Sabine Genth-Zotz and S. D. Anker and Hans - Dieter Volk}, journal={International journal of cardiology}, year={2002}, volume={85 1}, pages={173-83} }