Cachectin/tumor necrosis factor and interleukin-1 show different modes of combined effect on lipoprotein lipase activity and intracellular lipolysis in 3T3-L1 cells.

@article{Ogawa1989CachectintumorNF,
  title={Cachectin/tumor necrosis factor and interleukin-1 show different modes of combined effect on lipoprotein lipase activity and intracellular lipolysis in 3T3-L1 cells.},
  author={Hitoshi Ogawa and S\oren Lyhne Nielsen and Masanobu Kawakami},
  journal={Biochimica et biophysica acta},
  year={1989},
  volume={1003 2},
  pages={131-5}
}
Cachectin/tumor necrosis factor (cachectin/TNF) and interleukin-1 (IL-1) share many effects in various tissues and cells, including suppression of lipoprotein lipase (LPL) activity and enhancement of intracellular lipolysis. A possible interaction between cachectin/TNF and IL-1 in these lipase systems was studied in 3T3-L1 adipocytes. The two cytokines… CONTINUE READING