Cacao extracts suppress tryptophan degradation of mitogen-stimulated peripheral blood mononuclear cells.

@article{Jenny2009CacaoES,
  title={Cacao extracts suppress tryptophan degradation of mitogen-stimulated peripheral blood mononuclear cells.},
  author={Michael Jenny and Elisabeth Santer and Andrzej Klein and Maximilian Ledochowski and Harald Schennach and Florian {\"U}berall and Dietmer Fuchs},
  journal={Journal of ethnopharmacology},
  year={2009},
  volume={122 2},
  pages={261-7}
}
ETHNOPHARMACOLOGICAL RELEVANCE The fruits of Theobroma cacao L. (Sterculiaceae) have been used as food and a remedy for more than 4000 years. Today, about 100 therapeutic applications of cacao are described involving the gastrointestinal, nervous, cardiovascular and immune systems. Pro-inflammatory cytokine interferon-gamma and related biochemical pathways like tryptophan degradation by indoleamine 2,3-dioxygenase and neopterin formation are closely associated with the pathogenesis of such… CONTINUE READING
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