Cabergoline reverses cortical hyperexcitability in patients with restless legs syndrome.

@article{Nardone2006CabergolineRC,
  title={Cabergoline reverses cortical hyperexcitability in patients with restless legs syndrome.},
  author={Raffaele Nardone and Harald Ausserer and Arianna Bratti and Markus Covi and Piergiorgio Lochner and Roland Marth and Frediano Tezzon},
  journal={Acta neurologica Scandinavica},
  year={2006},
  volume={114 4},
  pages={244-9}
}
OBJECTIVE To reverse the profile of abnormal intracortical excitability in patients with restless legs syndrome (RLS) by administering the dopaminergic agonist cabergoline. METHODS The effects of this drug on motor cortex excitability were examined with a range of transcranial magnetic stimulation (TMS) protocols before and after administration of cabergoline over a period of 4 weeks in 14 patients with RLS and in 15 healthy volunteers. Measures of cortical excitability included central motor… CONTINUE READING