CaIPF14030 negatively modulates intracellular ATP levels during the development of azole resistance in Candida albicans

Abstract

Aim:Widespread and repeated use of azoles, particularly fluconazole, has led to the rapid development of azole resistance in Candida albicans. We investigated the role of CaIPF14030 during the development of azole resistance in C albicans.Methods:The expression of CaIPF14030 was measured by quantitative RT-PCR, and CaIPF14030 was disrupted by the hisG-URA3… (More)
DOI: 10.1038/aps.2010.232

Topics

6 Figures and Tables

Cite this paper

@inproceedings{Jia2011CaIPF14030NM, title={CaIPF14030 negatively modulates intracellular ATP levels during the development of azole resistance in Candida albicans}, author={Xin-ming Jia and Ying Wang and Jun-dong Zhang and Hong-yue Tan and Yuanying Jiang and Jun Gu}, booktitle={Acta Pharmacologica Sinica}, year={2011} }