CaAlg hydrogel containing bone morphogenetic protein 4-enhanced adipose-derived stem cells combined with osteochondral mosaicplasty facilitated the repair of large osteochondral defects

@article{Chen2019CaAlgHC,
  title={CaAlg hydrogel containing bone morphogenetic protein 4-enhanced adipose-derived stem cells combined with osteochondral mosaicplasty facilitated the repair of large osteochondral defects},
  author={Linxin Chen and Yuanyuan Shi and Xin Zhang and Xiaoqing Hu and Zhenxing Shao and Linghui Dai and Xiaodong Ju and Yingfang Ao and Jianquan Wang},
  journal={Knee Surgery, Sports Traumatology, Arthroscopy},
  year={2019},
  pages={1-11}
}
Cartilage repair presents a challenge to clinicians and researchers. A more effective procedure that can produce hyaline-like cartilage is needed for articular cartilage repair. Mosaic osteochondral grafts for large osteochondral defects often show poor integration between the grafts and the surrounding normal cartilage, leading to defective cracks filled with fibrous tissue instead of hyaline-like cartilage. In the present study, we aimed to repair the defective cracks with a calcium alginate… CONTINUE READING
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