Ca2 +‐mobilizing hormones elicit phosphatidylethanol accumulation via phospholipase D activation

@article{Bocckino1987Ca2H,
  title={Ca2 +‐mobilizing hormones elicit phosphatidylethanol accumulation via phospholipase D activation},
  author={Stephen B. Bocckino and P B Wilson and John H. Exton},
  journal={FEBS Letters},
  year={1987},
  volume={225}
}

Hormonal Regulation of Phospholipid Metabolism via G-Proteins: Phosphoinositide Phospholipase C and Phosphatidylcholine Phospholipase D

Many hormones, neurotransmitters, and growth factors produce their effects by inducing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdInsP2) in the plasma membranes of their target cells

Phosphatidylethanol formation in human platelets: evidence for thrombin-induced activation of phospholipase D.

  • R. Rubin
  • Biology, Chemistry
    Biochemical and biophysical research communications
  • 1988

Phorbol Esters Stimulate Phospholipase D Activity in C-6 Glioma Cells

It is demonstrated that TPA stimulates phospholipase D activity in cultured C-6 glioma cells and this increase was inhibited by ethanol.

Phorbol ester and vasopressin activate phospholipase D in leydig cells

Phospholipase D-derived Products in the Regulation of 12-O-Tetradecanoylphorbol-13-acetate-stimulated Prostaglandin Synthesis in Madin-Darby Canine Kidney Cells*

The demonstration that inhibition of TPA-induced PA formation inhibits Raf-1 translocation in MDCK cells suggests that PLD-derived PA or DG act as second messengers in the induction of PGHS-2 by PKC-dependent pathways.
...

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Water-soluble alcohols can markedly stimulate the liberation of choline from ultrasonically treated lecithin by phospholipase D, usually due to an increase in hydrolase activity although often the associated transferase activity contributes.

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