Ca2+ transients and cell shortening in diabetic rat ventricular myocytes.

@article{Noda1993Ca2TA,
  title={Ca2+ transients and cell shortening in diabetic rat ventricular myocytes.},
  author={Naoko Noda and Hideharu Hayashi and Hiroshi Satoh and Hajime Terada and Mayumi Hirano and A Kobayashi and Noriko Yamazaki},
  journal={Japanese circulation journal},
  year={1993},
  volume={57 5},
  pages={449-57}
}
To investigate the role of abnormal Ca2+ metabolism in the diminished contractile function of diabetic myocardium, we measured the Ca2+ transients and cell contraction of diabetic rat myocytes. Isolated diabetic (8 weeks after 40 mg/kg streptozotocin, i.v.) and normal myocytes were loaded with acetoxymethyl ester of indo-1 (indo-1/AM). Ca2+ transients and cell circumferential shortening were measured simultaneously, using high temporal resolution video image analysis. The diastolic base and… CONTINUE READING
17 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…