Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate.

@article{Stutzmann2003Ca2SI,
  title={Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate.},
  author={Grace E. Stutzmann and Frank M Laferla and Ian Parker},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2003},
  volume={23 3},
  pages={758-65}
}
IP(3)-mediated Ca(2+) release is a crucial neuronal signaling mechanism that has not been extensively characterized in the mammalian cerebral cortex. We used two-photon, video-rate microscopy to image Ca(2+) signals evoked by photoreleased IP(3) in pyramidal neurons of mouse prefrontal cortex. Ca(2+) responses to photoreleased IP(3) varied greatly between… CONTINUE READING