Ca2+ mobilization in adult rat cardiomyocytes by angiotensin type 1 and 2 receptors.

@article{Shao1998Ca2MI,
  title={Ca2+ mobilization in adult rat cardiomyocytes by angiotensin type 1 and 2 receptors.},
  author={Qiming Shao and Laura L Saward and Peter Zahradka and Naranjan S. Dhalla},
  journal={Biochemical pharmacology},
  year={1998},
  volume={55 9},
  pages={1413-8}
}
The role of angiotensin II (AngII) in the regulation of heart function under normal and pathological conditions has been well documented. Although two types of AngII receptors (AT1 and AT2 receptors) are found in equal proportions in the rat heart, most studies have focused primarily on AT1 receptor-coupled events. In this study, the contribution of both types of AngII receptors to cardiac function was evaluated by measuring intracellular calcium ([Ca2+]i) levels at ambient temperature in… CONTINUE READING

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