Ca2+ influx and the store-operated Ca2+ entry pathway undergo regulation during mouse oocyte maturation

@inproceedings{Cheon2013Ca2IA,
  title={Ca2+ influx and the store-operated Ca2+ entry pathway undergo regulation during mouse oocyte maturation},
  author={Banyoon Cheon and Hoi-Chang Lee and Takuya Wakai and Rafael A. Fissore},
  booktitle={Molecular biology of the cell},
  year={2013}
}
In preparation for fertilization, mammalian oocytes undergo optimization of the mechanisms that regulate calcium homeostasis. Among these changes is the increase in the content of the Ca(2+) stores ([Ca(2+)]ER), a process that requires Ca(2+) influx. Nevertheless, the mechanism(s) that mediates this influx remains obscure, although is known that [Ca(2+)]ER can regulate Ca(2+) influx via store-operated Ca(2+) entry (SOCE). We find that during maturation, as [Ca(2+)]ER increases, Ca(2+) influx… CONTINUE READING
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