Ca2+ homeostasis and apoptotic resistance of neuroendocrine-differentiated prostate cancer cells


AbstractNeuroendocrine (NE) differentiation is a hallmark of advanced, androgen-independent prostate cancer, for which there is no successful therapy. NE tumor cells are nonproliferating and escape apoptotic cell death; therefore, an understanding of the apoptotic status of the NE phenotype is imperative for the development of new therapies for prostate… (More)
DOI: 10.1038/sj.cdd.4401375


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