Ca2+ current versus Ca2+ channel cooperativity of exocytosis.

@article{Matveev2009Ca2CV,
  title={Ca2+ current versus Ca2+ channel cooperativity of exocytosis.},
  author={Victor Matveev and Richard Bertram and Arthur Sherman},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2009},
  volume={29 39},
  pages={12196-209}
}
Recently there has been significant interest and progress in the study of spatiotemporal dynamics of Ca(2+) that triggers exocytosis at a fast chemical synapse, which requires understanding the contribution of individual calcium channels to the release of a single vesicle. Experimental protocols provide insight into this question by probing the sensitivity of exocytosis to Ca(2+) influx. While varying extracellular or intracellular Ca(2+) concentration assesses the intrinsic biochemical Ca(2… CONTINUE READING