Ca2+ and BMP-6 Signaling Regulate E2F during Epidermal Keratinocyte Differentiation*

@article{Dsouza2001Ca2AB,
  title={Ca2+ and BMP-6 Signaling Regulate E2F during Epidermal Keratinocyte Differentiation*},
  author={S. Dsouza and A. Pająk and K. Balazsi and L. Dagnino},
  journal={The Journal of Biological Chemistry},
  year={2001},
  volume={276},
  pages={23531 - 23538}
}
  • S. Dsouza, A. Pająk, +1 author L. Dagnino
  • Published 2001
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • The epidermis consists of a squamous epithelium continuously replenished by committed stem cells, which can either self-renew or differentiate. We demonstrated previously that E2F genes are differentially expressed in developing epidermis (Dagnino, L., Fry, C. J., Bartley, S. M., Farnham, P., Gallie, B. L., and Phillips, R. A. (1997) Cell Growth Differ. 8, 553–563). Thus, we hypothesized that various E2F proteins likely play distinct growth regulatory roles in the undifferentiated stem cells… CONTINUE READING
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    References

    SHOWING 1-10 OF 65 REFERENCES
    Opposite Functions for E2F1 and E2F4 in Human Epidermal Keratinocyte Differentiation*
    • 58
    • PDF
    Expression patterns of the E2F family of transcription factors during murine epithelial development.
    • 64
    • PDF
    Signal transduction pathways controlling the switch between keratinocyte growth and differentiation.
    • G. P. Dotto
    • Medicine, Biology
    • Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists
    • 1999
    • 103
    Expression and growth inhibitory effect of decapentaplegic Vg-related protein 6: evidence for a regulatory role in keratinocyte differentiation.
    • 52
    • PDF