Ca2+ and AMPK both mediate stimulation of glucose transport by muscle contractions.

@article{Wright2004Ca2AA,
  title={Ca2+ and AMPK both mediate stimulation of glucose transport by muscle contractions.},
  author={David G. Wright and Kathleen A Hucker and John O. Holloszy and Dong Ho Han},
  journal={Diabetes},
  year={2004},
  volume={53 2},
  pages={330-5}
}
It is now generally accepted that activation of AMP-activated protein kinase (AMPK) is involved in the stimulation of glucose transport by muscle contractions. However, earlier studies provided evidence that increases in cytosolic Ca(2+) mediate the effect of muscle contractions on glucose transport. The purpose of this study was to test the hypothesis that both the increase in cytosolic Ca(2+) and the activation of AMPK are involved in the stimulation of glucose transport by muscle… CONTINUE READING
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