Ca2+-activated Cl- channel currents in rat ventral prostate epithelial cells.


BACKGROUND In many epithelial tissues, the Cl(-) efflux via Ca(2+)-activated Cl(-) channels (Cl(Ca)) play a key role for the fluid secretion. To elucidate the mechanism of prostatic fluid secretion, the properties of whole-cell chloride conductance were investigated. MATERIALS AND METHODS Rat prostate secretory epithelial cells (RPSECs) were isolated by… (More)


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