Ca2+/calmodulin-dependent protein kinase IV activates cysteine-rich protein 1 through adjacent CRE and CArG elements.

@article{Najwer2005Ca2calmodulindependentPK,
  title={Ca2+/calmodulin-dependent protein kinase IV activates cysteine-rich protein 1 through adjacent CRE and CArG elements.},
  author={Ida Najwer and B. Lilly},
  journal={American journal of physiology. Cell physiology},
  year={2005},
  volume={289 4},
  pages={
          C785-93
        }
}
  • Ida Najwer, B. Lilly
  • Published 2005
  • Biology, Medicine
  • American journal of physiology. Cell physiology
Smooth muscle-specific transcription is controlled by a multitude of transcriptional regulators that cooperate to drive expression in a temporospatial manner. Previous analysis of the cysteine-rich protein 1 (CRP1/Csrp) gene revealed an intronic enhancer that is sufficient for expression in arterial smooth muscle cells and requires a serum response factor-binding CArG element for activity. The presence of a CArG box in smooth muscle regulatory regions is practically invariant; however, it… Expand
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