Ca2+/Calmodulin Modulates TRPV1 Activation by Capsaicin


TRPV1 ion channels mediate the response to painful heat, extracellular acidosis, and capsaicin, the pungent extract from plants in the Capsicum family (hot chili peppers) (Szallasi, A., and P.M. Blumberg. 1999. Pharmacol. Rev. 51:159-212; Caterina, M.J., and D. Julius. 2001. Annu. Rev. Neurosci. 24:487-517). The convergence of these stimuli on TRPV1… (More)

7 Figures and Tables


  • Blog articles referencing this paper

  • Presentations referencing similar topics