Ca current facilitation during postrest recovery depends on Ca entry.

@article{Hryshko1990CaCF,
  title={Ca current facilitation during postrest recovery depends on Ca entry.},
  author={Larry V. Hryshko and Donald M. Bers},
  journal={The American journal of physiology},
  year={1990},
  volume={259 3 Pt 2},
  pages={H951-61}
}
Whole cell Ca current (ICa) recovery after periods of rest was examined in voltage-clamped rabbit ventricular myocytes with Na and K currents suppressed. To evaluate rest-dependent changes in ICa independent of the effects of sarcoplasmic reticular (SR) Ca release, the intracellular Ca ([Ca]i) transients were usually buffered by ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (10 mM) in the patch pipette. When voltage-clamp pulses were resumed (at 0.5 Hz) after a period of… CONTINUE READING

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