Ca 2 from One or Two Channels Controls Fusion of a Single Vesicle at the Frog Neuromuscular Junction

@inproceedings{Shahrezaei2006Ca2F,
  title={Ca 2 from One or Two Channels Controls Fusion of a Single Vesicle at the Frog Neuromuscular Junction},
  author={Vahid Shahrezaei and Alex Cao and Kerry R Delaney},
  year={2006}
}
Neurotransmitter release is triggered by the cooperative action of approximately five Ca 2 ions entering the presynaptic terminal through Ca 2 channels. Depending on the organization of the active zone (AZ), influx through one or many channels may be needed to cause fusion of a vesicle. Using a combination of experiments and modeling, we examined the number of channels that contribute Ca 2 for fusion of a single vesicle in a frog neuromuscular AZ. We compared Ca 2 influx to neurotransmitter… CONTINUE READING
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Control of synaptic strength and timing by the release-site Ca 2 signal

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