CYTOTOXICITY STUDIES OF LASALOCID AND SILIBININ IN RAT HEPATOMA CELL CULTURE

@inproceedings{Radko2011CYTOTOXICITYSO,
  title={CYTOTOXICITY STUDIES OF LASALOCID AND SILIBININ IN RAT HEPATOMA CELL CULTURE},
  author={Lidia Radko and Wojciech A Cybulski and Wojciech Rzeski},
  year={2011}
}
The cytoprotective effect of silibinin in course of cytotoxicity induced by lasalocid had been measured in rat hepatoma FaO cell line. In the course of the study, MTT test (cellular metabolism), coomassie brillant blue binding test CBB (total cellular proteins), and LDH release test (membrane integrity) were applied. In addition, changes in the cell morphology after 24 h treatment were observed by light microscopy. The effective concentrations, EC50 were quantified for each compound alone… CONTINUE READING

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