CYP2S1: a short review.

  title={CYP2S1: a short review.},
  author={Sirkku T. Saarikoski and Steven P Rivera and Oliver Hankinson and Kirsti Husgafvel-Pursiainen},
  journal={Toxicology and applied pharmacology},
  volume={207 2 Suppl},
A new member of the cytochrome P450 superfamily, CYP2S1, has recently been identified in human and mouse. In this paper, we review the data currently available for CYP2S1. The human CYP2S1 gene is located in chromosome 19q13.2 within a cluster including CYP2 family members CYP2A6, CYP2A13, CYP2B6, and CYP2F1. These genes also show the highest homology to the human CYP2S1. The gene has recently been found to harbor genetic polymorphism. CYP2S1 is inducible by dioxin, the induction being mediated… CONTINUE READING