CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population.

@article{Basma2013CYP2E1AN,
  title={CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population.},
  author={Hussein A Basma and Loulou Hassan Kobeissi and Michel E. Jabbour and Mohamad Ahmad Moussa and Hassan R Dhaini},
  journal={International journal of molecular epidemiology and genetics},
  year={2013},
  volume={4 4},
  pages={
          207-17
        }
}
Urinary bladder cancer incidence in Lebanon ranks among the highest in the world. Cytochrome P450 2E1 (CYP2E1), NAD(P)H quinone oxidoreductase1 (NQO1), and N-Acetyltransferase1 (NAT1), are drug-metabolizing enzymes (DMEs) involved in the metabolism of carcinogens, such as arylamines and heterocyclic amines, implicated in bladder cancer. The present study attempts to investigate the role of these DMEs genetic polymorphism in bladder cancer risk among Lebanese men. 54 cases and 106 controls were… CONTINUE READING
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DMEs and bladder cancer risk in Lebanese

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