CYP2D6 Genotype and Phenotype in Amerindians of Tepehuano Origin and Mestizos of Durango, Mexico

@article{SosaMacas2006CYP2D6GA,
  title={CYP2D6 Genotype and Phenotype in Amerindians of Tepehuano Origin and Mestizos of Durango, Mexico},
  author={M. Sosa-Mac{\'i}as and G. Elizondo and C. Flores-P{\'e}rez and J. Flores-P{\'e}rez and Francisco Bradley-Alvarez and R. E. Alan{\'i}s-Ba{\~n}uelos and I. Lares‐Asseff},
  journal={The Journal of Clinical Pharmacology},
  year={2006},
  volume={46}
}
Although the drug‐metabolizing enzyme CYP2D6 has been studied extensively in subjects of differing ethnicities, limited CYP2D6 pharmacogenetic data are available for the Amerindian population and Mestizos of Mexico. Dextromethorphan hydroxylation phenotype was studied in Tepehuano Amerindian (n = 58) and Mestizo (n = 88) subjects, and 195 individuals (85 Tepehuano Amerindians and 110 Mestizos) were genotyped by polymerase chain reaction‐restriction fragment length polymorphism methods to… Expand
Distribution of CYP2D6 and CYP2C19 polymorphisms associated with poor metabolizer phenotype in five Amerindian groups and western Mestizos from Mexico.
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References

SHOWING 1-10 OF 63 REFERENCES
Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile.
Genetic analysis of the CYP2D locus in relation to debrisoquine hydroxylation capacity in Korean, Japanese and Chinese subjects.
Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.
Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: Polymorphism in RFLP and DNA sequence of CYP2D6
...
1
2
3
4
5
...