CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir

@article{Bhat2014CYP1A1AC,
  title={CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir},
  author={Gulzar Ahmad Bhat and Idrees Ayoub Shah and Muzamil Ashraf Makhdoomi and Beenish Iqbal and Rumaisa Rafiq and Sumaiya Nabi and Akbar Masood and Mohd Maqbool Lone and Nazir Ahmad Dar},
  journal={Tumor Biology},
  year={2014},
  volume={35},
  pages={5323-5330}
}
The study analyzed the relationship between genetic polymorphisms of phase I xenobiotic metabolizing enzymes, cytochromes P450 (CYP) 1A1 and CYP2E1 and esophageal squamous cell carcinoma (ESCC) in Kashmir, India. The different genotypes of CYP1A1 and CYP2E1 were analyzed by polymerase chain reaction and restriction fragment length polymorphism in 526 ESCC cases and equal number of matched controls. Conditional logistic regression models were used to assess the association of various genotypes… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Gene-environment interactions in esophageal cancer.

Critical reviews in clinical laboratory sciences • 2015

References

Publications referenced by this paper.
Showing 1-10 of 50 references

a laboratory manual

J Sambrook, Russell D. Molecular cloning
3rd ed. New York: Cold Spring Harbor Laboratory Press; 2001. Table 4 Results for gene–gene and gene–environment interaction Risk factor Standard error P value OR 95 % CI Smoking 0.29 0.99 0.99 0.56–1.77 CYP1A1 smoking 0.17 0.043 1.31 1.01–1.69 CYP2E1 smoking 0.14 0.827 0.97 0.74–1.27 CYP1A1 2E1 0. • 2014
View 1 Excerpt

Family history of cancer and the risk of cancer: a network of case-control studies.

Annals of oncology : official journal of the European Society for Medical Oncology • 2013

Cancer in Kashmir, India: burden and pattern of disease.

Journal of cancer research and therapeutics • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…