CYP1A1, CYP2E1, and GSTM1 gene polymorphisms and susceptibility to colorectal and gastric cancer among Lebanese.

@article{Darazy2011CYP1A1CA,
  title={CYP1A1, CYP2E1, and GSTM1 gene polymorphisms and susceptibility to colorectal and gastric cancer among Lebanese.},
  author={Mohamad Darazy and Mahmoud Balbaa and Anas M Mugharbil and Hesham Mahmoud Saeed and Hassan Sidani and Ziad Abdel-Razzak},
  journal={Genetic testing and molecular biomarkers},
  year={2011},
  volume={15 6},
  pages={423-9}
}
Mutations in the genes encoding enzymes involved in the metabolism of chemical carcinogens can significantly affect the risk of cell transformation and cancer development. The resident Lebanese population has experienced a sharp increase in cancer incidence within the last few years. The relationship between gene polymorphisms of metabolic enzymes and gastrointestinal (GI) cancer incidence was not previously investigated. The aim of this study was to investigate the relationship between CYP1A1… CONTINUE READING

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