CYK4 inhibits Rac1-dependent PAK1 and ARHGEF7 effector pathways during cytokinesis

@inproceedings{Bastos2012CYK4IR,
  title={CYK4 inhibits Rac1-dependent PAK1 and ARHGEF7 effector pathways during cytokinesis},
  author={Ricardo Nunes Bastos and Xenia Pe{\~n}ate and Michelle Bates and Dean Hammond and Francis A Barr},
  booktitle={The Journal of cell biology},
  year={2012}
}
In mitosis, animal cells lose their adhesion to the surrounding surfaces and become rounded. During mitotic exit, they reestablish these adhesions and at the same time physically contract and divide. How these competing processes are spatially segregated at the cell cortex remains mysterious. To address this question, we define the specific effector pathways used by RhoA and Rac1 in mitotic cells. We demonstrate that the MKlp1-CYK4 centralspindlin complex is a guanosine triphosphatase… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
29 Citations
53 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Similar Papers

Loading similar papers…