CXCR7 mediates SDF1-induced melanocyte migration.

  title={CXCR7 mediates SDF1-induced melanocyte migration.},
  author={Eunkyung G. Lee and Jiyeon Han and Kwangmi Ko Kim and Hyunjung Choi and Eun-Gyung Cho and Tae Ryong Lee},
  journal={Pigment cell & melanoma research},
  volume={26 1},
Melanoblasts are derived from the neural crest and migrate to the dermal/epidermal border of skin and hair bulges. Although melanoblast migration during embryogenesis has been well investigated, there are only a few reports regarding the migration of mature melanocytes. Here, we demonstrate that a chemokine, stromal-derived factor-1 (SDF1, also known as CXCL12), and one of its receptor CXCR7 regulate normal human epidermal melanocyte (NHEM) migration. We found that SDF1 induces the directional… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
14 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…