CXCR4 expression in feline mammary carcinoma cells: evidence of a proliferative role for the SDF-1/CXCR4 axis

@inproceedings{Ferrari2012CXCR4EI,
  title={CXCR4 expression in feline mammary carcinoma cells: evidence of a proliferative role for the SDF-1/CXCR4 axis},
  author={Angelo Ferrari and Claudio Petterino and Alessandra Ratto and Chiara Campanella and Roberto Wurth and Stefano Thellung and Guendalina Vito and Federica Barbieri and Tullio Florio},
  booktitle={BMC veterinary research},
  year={2012}
}
BACKGROUND Mammary tumours frequently develop in female domestic cats being highly malignant in a large percentage of cases. Chemokines regulate many physiological and pathological processes including organogenesis, chemotaxis of inflammatory cells, as well as tumour progression and metastasization. In particular, the chemokine/receptor pair SDF-1/CXCR4 has been involved in the regulation of metastatic potential of neoplastic cells, including breast cancer. The aim of this study was the… CONTINUE READING

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