CXCR4 and NMDA Receptors Are Functionally Coupled in Rat Hippocampal Noradrenergic and Glutamatergic Nerve Endings

Abstract

Previous studies had shown that the HIV-1 capsidic glycoprotein gp120 (strain IIIB) modulates presynaptic release-regulating NMDA receptors on noradrenergic and glutamatergic terminals. This study aims to assess whether the chemokine CXC4 receptors (CXCR4s) has a role in the gp120-mediated effects. The effect of CXCL12, the endogenous ligand at CXCR4, on… (More)
DOI: 10.1007/s11481-016-9677-6

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Cite this paper

@article{Prisco2016CXCR4AN, title={CXCR4 and NMDA Receptors Are Functionally Coupled in Rat Hippocampal Noradrenergic and Glutamatergic Nerve Endings}, author={Silvia Di Prisco and Guendalina Olivero and Elisa Merega and Tommaso Bonfiglio and Mario Marchi and Anna Pittaluga}, journal={Journal of Neuroimmune Pharmacology}, year={2016}, volume={11}, pages={645-656} }