CXCR4 Expression in Prostate Cancer Progenitor Cells

Abstract

Tumor progenitor cells represent a population of drug-resistant cells that can survive conventional chemotherapy and lead to tumor relapse. However, little is known of the role of tumor progenitors in prostate cancer metastasis. The studies reported herein show that the CXCR4/CXCL12 axis, a key regulator of tumor dissemination, plays a role in the… (More)
DOI: 10.1371/journal.pone.0031226

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