CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis.

Abstract

Regional differences in inflammation during viral infections of the CNS suggest viruses differentially induce patterns of chemoattractant expression, depending on their cellular targets. Previous studies have shown that expression of the chemokine CXCL10 by West Nile virus (WNV)-infected neurons is essential for the recruitment of CD8 T cells for the… (More)

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