CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity.

@article{Takahashi2007CXCL14EI,
  title={CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity.},
  author={Michiko Takahashi and Yutaka Takahashi and Kenichi Takahashi and Fyodor N. Zolotaryov and Kyoung Su Hong and Keiji Iida and Yasuhiko Okimura and Hidesuke Kaji and Kazuo Chihara},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={364 4},
  pages={1037-42}
}
Accumulating evidence suggests an association between obesity and adipose tissue inflammation. Chemokines are involved in the regulation of inflammation status. Chemokine (C-X-C motif) ligand 14 (CXCL14) is known to be a chemoattractant for monocyte and dendritic cells. Recently, it was reported that CXCL14-deficient mice show resistance to high-fat diet-induced obesity. In this study, we identified CXCL14 as a growth hormone (GH)-induced gene in HepG2 hepatoma cells. Substantial in vivo… CONTINUE READING

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