CXCL13–CXCR5 co-expression regulates epithelial to mesenchymal transition of breast cancer cells during lymph node metastasis

@article{Biswas2013CXCL13CXCR5CR,
  title={CXCL13–CXCR5 co-expression regulates epithelial to mesenchymal transition of breast cancer cells during lymph node metastasis},
  author={S. Biswas and Suman Sengupta and S. Roy Chowdhury and Samir Jana and G. Mandal and P. Mandal and N. Saha and V. Malhotra and Arnab Gupta and D. Kuprash and A. Bhattacharyya},
  journal={Breast Cancer Research and Treatment},
  year={2013},
  volume={143},
  pages={265-276}
}
We investigated the expression of –CXC chemokine ligand 13 (CXCL13) and its receptor –CXC chemokine receptor 5 (CXCR5) in 98 breast cancer (BC) patients with infiltrating duct carcinoma, out of which 56 were found lymph node metastasis (LNM) positive. Interestingly, co-expression of CXCL13 and CXCR5 showed a significant correlation with LNM. Since, epithelial to mesenchymal transition (EMT) is highly associated with metastasis we investigated EMT-inducing potential of CXCL13 in BC cell lines… Expand
A Novel ACKR2-Dependent Role of Fibroblast-Derived CXCL14 in Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer
CXCL13-CXCR5 axis promotes the growth and invasion of colon cancer cells via PI3K/AKT pathway
Signaling via the CXCR5/ERK pathway is mediated by CXCL13 in mice with breast cancer.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 57 REFERENCES
Antibody Microarray Analysis of Signaling Networks Regulated by Cxcl13 and Cxcr5 in Prostate Cancer.
Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines
Role of CXCL1 in tumorigenesis of melanoma
...
1
2
3
4
5
...