CXCL12/CXCR4 axis induces proliferation and invasion in human endometrial cancer.

OBJECTIVE Since that we have previously found CXCL12/CXCR4, an important biological axis is highly transcribed in several cancer cells. We aim to investigate whether CXCL12/CXCR4 axis regulates critical processes in neoplastic transformation that affects endometrial cancer cell biology. METHODS The expression levels of CXCR4 were analyzed in human normal… CONTINUE READING