CXC chemokine suppression of polymorphonuclear leukocytes apoptosis and preservation of function is oxidative stress independent.

Abstract

Interleukin 8 (IL-8) and growth-related oncogene alpha (Gro-alpha) delay neutrophil apoptosis, which is thought to be important for the resolution of inflammation. We hypothesized that (IL-8) and Gro-alpha interfere with extracellular death receptor signaling or intracellular caspase activation to suppress neutrophil apoptosis. In addition, we sought to… (More)

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Cite this paper

@article{Dunican2000CXCCS, title={CXC chemokine suppression of polymorphonuclear leukocytes apoptosis and preservation of function is oxidative stress independent.}, author={A L Dunican and S J Leuenroth and Alfred Ayala and H. Hank Simms}, journal={Shock}, year={2000}, volume={13 3}, pages={244-50} }